Tag: phospholipid

Antiphospholipid Antibodies: Discussion

Therefore, the presence of immune type aPL is thought to be responsible for the occurrence of thrombotic complications because foGPI is a well-known plasma protein with anticoagulant activity. The enzyme-linked immunosorbent assay method we applied in the present study for the detection of aPL can detect these two types of aPL, but cannot distinguish them….

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Antiphospholipid Antibodies: Analysis

There were 23 cases in which abnormal chest x-ray film findings disappeared within 2 years, but 23 cases in which these findings persisted for over 2 years. The aPL frequency was 13 percent (3 of 23) in the former group and 65 percent (15 of 23) in the latter. Nine cases not included in this…

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Antiphospholipid Antibodies: Results

Frequency of Antiphospholipid Antibodies Twenty-one (9 male and 12 female) of 55 (38 percent) cases of sarcoidosis had aPL (IgG or IgM aPL or both). In contrast, only 5 (7 percent) of 70 cases in the control group were positive for aPL. The presence of aPL was significantly higher (p<0.01) in patients with sarcoidosis (Fig…

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Antiphospholipid Antibodies: Methods

The IgG and IgM antibodies against each phospholipid were measured by an enzyme-linked immunosorbent assay method. Microtiter plates were coated with each type of phospholipid and diluted with methanol to 50 Mg/ml. After drying at 50°C for 30 min and washing 3 times in 0.01 mol/L phosphate-buffered saline (PBS), 50 Mg/ml of 10 percent bovine…

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Antiphospholipid Antibodies: Materials

Sarcoidosis is a systemic disease of unknown cause characterized by the presence of non-caseating epithelioid cell granulomas in affected organs and shows a variety of clinical courses. It is well-known that patients with sarcoidosis have humoral immunologic abnormalities. Canadian helth& care mall Increases in serum immunoglobulin and complications of autoimmune diseases also have been reported….

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