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Prevalence and Correlates of Restless Legs Syndrome: Recommendation

Prevalence and Correlates of Restless Legs Syndrome: RecommendationThe findings of the NSF 2005 poll in comparison to the REST study highlight the importance of frequency criteria. If RLS risk is defined to include a requirement for symptoms every night or almost every night, as well as for symptoms being worse at night, the prevalence is lower. Most clinical definitions of RLS do not have specific frequency criteria, which has probably contributed to some variance in prevalence estimates. This may also be part of the reason that RLS has been diagnosed and treated in far < 10% of the population, as it is likely that many physicians and patients are unwilling to undertake long-term treatment for symptoms that are not frequent.
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Prevalence and Correlates of Restless Legs Syndrome: Conclusion

It is also very current, having been conducted in late 2004, while the data from the Third National Health and Nutrition Examination Survey were collected more than a decade ago. The age ranges and definitions of geographic areas covered by each study are different. Yet, the findings are striking, since both anemia and RLS symptoms appear to be more prevalent in the south. While this association can be considered hypothesis-generating at best, it supports the biological basis of iron deficiency as a factor in the pathogenesis RLS. We found a tendency for the endorsement of RLS symptoms to increase with age until the age of 65 years, as has been reported by others,” and we noted a trend toward increased prevalence in women compared with men. We also confirmed the association between RLS symptoms and both cigarette smoking and being overweight. There was a strong association between physical and mental health problems and RLS symptoms, as has consistently been reported by others.’ this

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Prevalence and Correlates of Restless Legs Syndrome: Discussion

Prevalence and Correlates of Restless Legs Syndrome: DiscussionThose patients who endorsed RLS symptoms appeared to experience significantly more daytime problems (Fig 2), including being late to work, making errors at work, or missing work because of sleepiness. They also reported missing events and driving drowsy more frequently than did other respondents in the poll (p < 0.05 for all). Fifty-five percent of men and 45% of respondents reported twitching or moving their bodies frequently at night, and those who did so were more likely to be from the south.
New findings in this study are a reduced risk of RLS symptoms for those in the northeastern United States, and the association of the risk of RLS with the risk for sleep apnea and impaired daytime performance. Reading here

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Prevalence and Correlates of Restless Legs Syndrome: Results

A striking finding of the poll results was the marked regional variation in prevalence of RLS symptoms (Fig 1). Those patients from the northeastern United States were statistically less likely to be at risk for RLS than those from other areas (p < 0.05). Those from the south were about twice as likely to have frequent or occasional symptoms of RLS than those from any other region; when we analyzed the data comparing those patients who had uncomfortable leg sensations every night or almost every night, those from the south were statistically significantly more likely than those from other geographic areas to be in this group (p < 0.05). Several lifestyle factors were associated with RLS symptoms; those who reported being unemployed and being cigarette smokers were more likely to report RLS symptoms (p < 0.05). The presence of many of the medical conditions included in the NSF survey, including hypertension, arthritis, gastroesophageal reflux disease, depression, anxiety, and diabetes were associated with an endorsement of RLS symptoms (p < 0.05); there was a trend (p < 0.10) for endorsement of RLS symptoms by those with heart and lung disease. read only

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Prevalence and Correlates of Restless Legs Syndrome: Analysis of NSF Poll

Prevalence and Correlates of Restless Legs Syndrome: Analysis of NSF PollStatistical analyses included x2 tests of associations for age and sex group differences in the percentage for each sleep problem. Those who endorsed symptoms of uncomfortable leg sensations every night, almost every night, or a few nights a week or more and who reported that these symptoms were worse at night were designated as being “at risk for RLS.” Stepwise multiple logistic regression models were used to predict the odds for each sleep problem according to significantly associated medical conditions after adjusting for age, gender, and an existing diagnosis of a sleep disorder. A multidimensional multiple logistic regression for the odds of reporting one or more sleep problems was derived from the various indexes for diseases, health, and behavioral characteristics. Analyses were performed with a statistical software package (SAS; SAS Institute; Cary, NC). read

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Prevalence and Correlates of Restless Legs Syndrome: Materials

Participants were also asked “In the past year, according to your own experiences or what others tell you, how often did you move your body frequently or have twitches often during the night?” In addition, they were queried about usual bedtimes and wake times on weekdays vs weekends and their usual number of hours of sleep on those days. Respondents were also asked how often in the past year they had difficulty falling asleep, were awake a lot during the night, woke up too early and could not get back to sleep, woke up feeling unrefreshed, snored, had pauses in breathing during sleep, or how often they feel tired or fatigued or not up to par during wake time. Frequency responses for these items were every night or almost every night, a few nights a week, a few nights a month, rarely, or never. Persons reporting these symptoms a few nights a week or more were labeled as having the particular sleep problems/disorder. read more

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Prevalence and Correlates of Restless Legs Syndrome: Methods

Prevalence and Correlates of Restless Legs Syndrome: MethodsThus, the participation rate calculated by taking the number of completed interviews divided by the number of completed interviews plus the number of contacted households who refused participation or did not qualify was 23%. Institutional review board approval was not required to conduct or publish the results of a poll without any individual identifying information that is conducted by a nonprofit independent organization. There was no compensation for participation. Here

Approximately 80% of the interviews were conducted on weekdays between 5:00 pm and 8:00 pm, on Saturdays between 10:00 am and 4:00 pm, and on Sundays between 4:00 pm and 8:00 pm by professional interviewers from WB&A Market Research (Annapolis, MD) on behalf of the NSF.
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Prevalence and Correlates of Restless Legs Syndrome: NSF Poll

The NSF conducts Sleep in America polls annually, with the release of the results timed to coincide with National Sleep Awareness Week, which is the week before the change to Daylight Savings time in the spring. The topics and questions included in the poll are selected by a subset of volunteers and board members, and there is no commercial or industry influence on this poll. Since the diagnosis of RLS is made on the basis of a history of uncomfortable leg sensations that are worsened with inactivity and occur at night, it is possible and appropriate to learn about the prevalence and risks of this cluster of symptoms in a survey of sleep habits. To date, no random sample of RLS prevalence specifically in the US population has been undertaken. inhalers for asthma

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Prevalence and Correlates of Restless Legs Syndrome

Prevalence and Correlates of Restless Legs SyndromeRestless legs syndrome (RLS) is a common, debilitating condition. The prevalence of RLS is estimated to be about 10% and increases with age. Women appear to be at increased risk, as do individuals with certain chronic conditions, including renal failure and anemia. The pathophysiology of RLS is incompletely understood, but it probably results from derangements in dopamine and iron metabolism, and has a genetic component.’’ It appears likely that a majority of individuals with RLS do not seek or receive medical attention. Because RLS is a prevalent sleep disorder, it is likely to be encountered by pulmonologists who are practicing sleep medicine. ventolin inhalers

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