Regional variations in risk factors for asthma in school children: RESULTS (4)

Regional variations in risk factors for asthma in school children: RESULTS (4)These associations were not significant in Swift Current. Although there was an increased risk of asthma in both communities if the child had previous ETS exposure from the mother (Swift Current: OR=1.87, 95% CI 1.06 to 3.30; Estevan: OR=2.00, 95% CI 1.17 to 3.43), there was an inverse association between asthma and current ETS exposure in Estevan that was borderline significant (OR=0.64, 95% CI 0.40 to 1.00), and there was no significant association between asthma and mother’s current smoking in Swift Current.
Stratified analysis by sex
The final multivariate model was fitted separately for boys and girls (Table 5). In both boys and girls, respiratory allergy, family history of asthma and early childhood respiratory illness were associated with asthma — asthma inhalers. The association between asthma and past ETS exposure from the mother was significant in boys. In girls, the association between rural living and asthma was significant. Also in girls, the association between asthma and home mould or dampness was significant between towns, with girls showing a significant increase in the risk of asthma with the report of home mould or dampness in Estevan but not Swift Current.

TABLE 5 Multivariate logistic regression model of risk factors for asthma stratified by sex

Boys (n=1025) Girls (n=1013)
OR (95% CI) P OR (95% CI) P
Age 0.97 (0.88-1.07) 0.49 0.97 (0.86-1.09) 0.57
Respiratory allergy
Absent 1.00 1.00
Present 8.28 (5.83-11.76) <0.001 9.43 (6.28-14.17) <0.001
Early childhood respiratory illness
Absent 1.00 1.00
Present 2.31 (1.43-3.72) 0.001 3.28 (1.89-5.68) <0.001
Family history of asthma
Absent 1.00 1.00
Present 2.73 (1.68-4.44) <0.001 2.03 (1.22-3.38) 0.006
ETS exposure from the mother
None 1.00 1.00
Past 2.04 (1.19-3.50) 0.01 1.76 (0.97-3.20) 0.06
Current 0.98 (0.64-1.50) 0.87 0.84 (0.51-1.38) 0.50
ETS exposure from the father
None 1.00 1.00
Past 1.10 (0.62-1.94) 0.75 1.15 (0.61-2.14) 0.67
Current 0.94 (0.62-1.41) 0.75 0.85 (0.53-1.37) 0.51
Residence
Urban 1.00 1.00
Rural 0.84 (0.35-2.02) 0.70 2.91 (1.44-5.90) 0.003
Air conditioning
Absent 1.00 1.00
Present 0.75 (0.52-1.10) 0.14 0.95 (0.62-1.45) 0.95
Dwelling type
Single-family house 1.00 1.00
Other dwelling type 1.16 (0.70-1.92) 0.57 1.53 (0.88-2.67) 0.13
Home mould or dampness
Swift Current (absent) 1.00 1.00
Swift Current (present) 0.97 (0.53-1.79) >0.05 0.64 (0.31-1.31) >0.05
Estevan (present) 1.70 (0.98-2.94) >0.05 1.76 (1.01-3.07) <0.05
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