Regional variations in risk factors for asthma in school children: DISCUSSION (4)

Regional variations in risk factors for asthma in school children: DISCUSSION (4)Hessel et al and Duhme et al have shown that environmental factors are not consistently associated with asthma across different locations within the same study. Although our study supports this, some of the significant associations between asthma and environmental factors differed between our study and that of Hessel et al and Duhme et al. These inconsistencies could be due to differences in methods or variations in settings. Buy Asthma Inhalers Online
Hessel et al conducted a cross-sectional study followed by a case-control study in two Canadian communities from a similar region. A stratified, multivariate analysis showed differences in the association between various risk factors and asthma between communities. Although Hessel et al focused on a sample of the population, we were able to approach all eligible school children within each study community, and experienced excellent participation rates from both communities. In addition, our study focused on a narrower age range (six to 13 years) compared with the study by Hessel et al (five to 19 years), which could reduce potential confounding factors such as a personal smoking history with older children. In a cross-sectional study by Duhme et al in Germany, associations with asthma were studied in two communities with differences in the associations between communities being seen for five- to eight-year-old children; however, the two communities being compared were from different regions (one was a coastal city and the other was an inland city).

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