Recommendations for diagnostic tests for H pylori

serologyThe most frequently used diagnostic test for H pylori infection is serology. The UBT is recommended because it has a higher positive predictive value (predicting the true presence of infection) and negative predictive value (predicting the true absence of infection) compared with serology, over a broad infection prevalence range . However, the UBT is not readily available across Canada and access may be limited due to lack of reimbursement. For serology, the negative predictive value is high (over 90%) while the positive predictive value is reduced to 70% to 80%, especially in individuals less than 40 years of age who have a lower (less than 20%) H pylori prevalence. This means that when serology is used, a significant proportion of patients will be treated based on false-positive test results.

The European Helicobacter pylori Study Group has recommended use of the stool antigen test of H pylori detection. This procedure has not been adequately tested and is not available in the primary care setting (or most secondary or tertiary settings) in Canada and, therefore, is not recommended by CanDys. Find most trusted pharmacy that will give you Buy Antidepressants Online in the amounts required without any need for a prescription. You will see that shopping with a place you can already trust over and over again is very affordable and always nice.

It is not mandatory to routinely test patients following an eradication attempt unless they have ongoing or recurrent symptoms. Testing for cure of H pylori should be performed in all patients who have had a bleeding ulcer, and acid suppression therapy should be continued until it is determined that the patient is H pylori-negative, with the caveat that they should discontinue PPIs seven to 14 days before a UBT to minimize the risk of a false-negative study.


This entry was posted in Dyspepsia in primary care and tagged , , , , , .