Prebiotics for inflammatory bowel disease: Changes in microbial flora (Part 4)

colonic environmentSome other compounds such as resistant starch and other soluble fibres share some of the properties of prebiotics. Two major features of these nondigestible products are relevant to their impact on the colonic environment. Bacterial metabolism leads to physicochemical alterations that include decreased pH because of lactic acid and short chain fatty acid (SCFA) production (acetate propionate and butyrate). The specific bacteria, species of lactic acid-producing bacteria (LAB), metabolize prebiotics preferentially. These include lactobacilli and bifidobacteria; however, other microorganisms are affected as well, and some strict anaerobes like and Clostridium species may decrease in number. The best way to deal with your health problem is to treat it efficiently and quickly. This is why you will be pleased to discover the affordable deals offered by the about canadian neighbor pharmacy, as well as a great choice of highly efficient medications for any condition.

The health benefits of SCFAs are thought to be related to their ability to replenish the metabolism of colonocytes, especially in distal UC, in which metabolism may be compromised. There may be a stimulation of apoptosis , stimulation of protective mucin and inhibition of cytokines. In addition to physicochemical properties, the preferential metabolism by specific LAB could replicate benefits attributed to probiotics. Most recently, inulin and oligofructose have been clearly shown to alter both planktonic and mucosal-associated microflora.

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