Category Archives: Smoker

Impaired Quality of Life of Healthy Young Smokers: Conclusion

Hypothetical explanations for the HRQL decreases may be initially sought in cigarette consumption itself. Smoking produces thousands of chemicals that are absorbed through the lungs. Some substances could have organic actions leading to asthenia, vitality loss, muscle disorders, or psychological derangement. Nicotine, for example, induces tachycardia and peripheral vasoconstriction. Decreases in peripheral blood flow may potentially interfere with tissue metabolism, impairing task performance. In addition, elevations of carbon monoxide and car-boxyhemoglobin may also impair tissue oxygenation. The findings that smoking may impair cardiorespiratory variables and decrease maximal oxygen uptake during exercise tests support this hypothesis. However, an additional comparison in our data between the SF-36 scores of heavy and moderate smokers with those of the light smokers did not show any significant difference between the groups. This suggests that the HRQL impairments of young smokers do not appear to be influenced by the smoking intensity, and argues against a functional cause for the present results. Continue reading

Impaired Quality of Life of Healthy Young Smokers: Discussion

Impaired Quality of Life of Healthy Young Smokers: DiscussionThe never-smoker group showed higher mean quality-of-life scores than the smoker group in all domains (Table 2). Smoking was significantly associated with lower scores in all quality-of-life parameters except physical role, pain index, and emotional role. The comparison of the emotional role domain was marginally significant (p = 0.0576). The statistical analysis showed no influence of a history of alcohol consumption on the results. Continue reading

Impaired Quality of Life of Healthy Young Smokers: Results

The obtained forms were classified in two groups: smokers and never-smokers. A smoker was defined as a person who had smoked at least one cigarette every day during the last month. Only forms from subjects

Two hundred seventy-nine students answered the forms. One hundred twelve subjects (40%) were smokers and 167 were never-smokers. One hundred five forms (38%) had to be excluded from analysis due to age > 25 years, presence of health conditions, chronic use of medications, and drug abuse. The final groups were composed by 77 smokers and 97 never-smokers.
Clinical features of both groups are listed in Table 1. Smokers started smoking at a mean age of 17.5 years (SD, 2.6). The mean smoking duration and intensity were 3.2 years (SD, 2.1) and 1.7 pack-years (SD, 1.8), respectively. Fifty-seven subjects could be classified as light smokers ( 25 cigarettes/d). avandia generic
A substantial number of volunteers reported regular use of alcoholic beverages, especially beer. The smokers group showed a significantly higher proportion of subjects reporting alcohol consumption than never-smokers (70% vs 48.5%).

Table 1—Clinical Features of Healthy Young Students





Male/female gender No.






Age, yr

20.5 (2.0)

20.6 (2.0)

Smoking duration, yr

3.2 (2.1)

Smoking intensity, pack-yr

1.7 (1.8)

Alcohol consumption, No. (%)t

54 (70)

47 (48.5)

Impaired Quality of Life of Healthy Young Smokers

Impaired Quality of Life of Healthy Young SmokersSome studies have shown that smoking may lead to impairment of health-related quality of life (HRQL). Significant differences in mean scores, as measured by the 36-item short form (SF-36), have been observed between never-smokers, smokers, and ex-smokers in population surveys. Similar results were obtained employing the St. George’s Respiratory Questionnaire in a group of subjects older than 55 years. there
The results of general population surveys and studies including old people can be potentially influenced by unrecognized smoking-related disorders and other comorbidities. So far, no investigation has been done specifically aimed at investigating HRQL in young subjects with a short smoking history. The objective of the present study was to investigate HRQL in a selected sample of healthy young smokers. Continue reading